نتایج جستجو برای: CETP polymorphism

تعداد نتایج: 108180  

Journal: :The Indian journal of medical research 2009
Taghi Hassanzadeh Mohsen Firoozrai Abdolvahhab Ehsani Zonouz Abbas Zavarehee Max Paoli

BACKGROUND & OBJECTIVE Cholesteryl ester transfer protein (CETP) gene polymorphism is known to be associated with changes in lipid profiles. Primary hyperlipidaemia is considered to be a major risk factor for pancreatitis, atherosclerosis and coronary heart disease. We investigated the association of one common polymorphism in the CETP gene (Taq1B) with plasma lipid levels and CETP activity in ...

برخورداری, عسگر, حسن زاده, تقی, فتاحی, امیر, لطیفی, زینب, سعیدی جم, مسعود ,

Introduction & Objective: It has been shown that there is a correlation between cholesterol con-centration and coronary heart disease (CHD). Cholesteryl ester transfer protein (CETP) plays a central role in lipoproteins metabolism and it has been suggested that various polymorphisms in CETP gene can affect the enzyme activity and blood lipid parameters. There was not enough information about ...

Effat Farrokhi, Keihan Ghatreh Samani, Masoud Darabi Amin, Mohammad Noori, Mohammad Rohbani Nobar, Morteza Hashemzadeh Chaleshtori,

Background: Cholesteryl ester transfer protein (CETP) plays a main role in high-density lipoprotein metabolism. CETP gene possesses several single nucleotide polymorphisms which have been associated with plasma high-density lipoprotein cholesterol (HDL-C) concentrations. The aim of this study was to determine the association of CETP -629C/A and I405V polymorphisms with coronary artery disease (...

2016
Marta Włodarczyk Małgorzata Wrzosek Grażyna Nowicka Beata Jabłonowska-Lietz

INTRODUCTION Polymorphisms in the cholesterol ester transfer protein (CETP) gene and apolipoprotein AI (apo AI) gene are identified as the most common genetic factors influencing high-density lipoprotein cholesterol (HDL cholesterol) levels. Low HDL cholesterol is an important risk factor for cardiovascular disease. We investigated the effect of the TaqIB polymorphism of the CETP gene and the 7...

اسماعیلی, رسول, برخورداری, عسگر, حسن‌زاده, تقی, سعیدی جم, مسعود, پائولی, مکس,

Background: Hypercholesterolemia is considered a major risk factor for pancreatitis, atherosclerosis and coronary heart disease. Cholesteryl ester transfer protein gene polymorphisms are known to be associated with changes in lipid levels. We investigated the association between a polymorphism in the CETP gene (D442G) with plasma lipid levels and CETP activity in patients with hypercholesterole...

Journal: :medical laboratory journal 0
mohammadzadeh, ghorban hyperlipidemia research center, faculty of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran karimpour, fatemeh faculty of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran ghaffari, mohammad ali cellular and molecular research center, faculty of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran kheirollah, alireza cellular and molecular research center, faculty of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran saki, azadeh school of public health, ahvaz jundishapur university of medical sciences, ahvaz, iran

abstract      background and objective: diabetes mellitus is the most common risk factor for coronary artery disease (cad). cholesteryl ester transfer protein (cetp) taqib polymorphism is associated with changes in lipid profile and may be a risk factor for cad in patients with diabetes. this study aimed to evaluate the association of cetp taqib polymorphism with cad in patients with type 2 dia...

Journal: :Aging cell 2012
Lei Yu Joshua M Shulman Lori Chibnik Sue Leurgans Julie A Schneider Philip L De Jager David A Bennett

The cholesteryl ester transfer protein (CETP) gene plays an essential role in regulating cholesterol homeostasis and is a candidate susceptibility gene for late-onset Alzheimer's disease (AD). Recent finding suggests that the CETP I405V polymorphism (rs5882) is associated with a slower rate of memory decline and a lower risk of incident dementia. Using data from two ongoing epidemiologic clinic...

Journal: :Journal of the American College of Cardiology 2003
Stefan Blankenberg Hans J Rupprecht Christoph Bickel Xian-Cheng Jiang Odette Poirier Karl J Lackner Jürgen Meyer François Cambien Laurence Tiret

OBJECTIVES We sought to evaluate the association between cholesteryl ester transfer protein (CETP) genotypes and the risk of future cardiovascular mortality in patients with coronary artery disease (CAD). BACKGROUND Polymorphisms of the CETP gene influence CETP activity and high-density lipoprotein (HDL) cholesterol concentration and might affect the long-term prognosis and response to statin...

Journal: :iranian biomedical journal 0
کیهان قطره ثمانی keihan ghatreh samani محمد نوری mohammad noori محمد رهبانی نوبر mohammad rohbani nobar مرتضی هاشم زاده چالشتری morteza hashemzadeh chaleshtori عفت فرخی effat farrokhi مسعود دارابی امین masoud darabi amin

background: cholesteryl ester transfer protein (cetp) plays a main role in high-density lipoprotein metabolism. cetp gene possesses several single nucleotide polymorphisms which have been associated with plasma high-density lipoprotein cholesterol (hdl-c) concentrations. the aim of this study was to determine the association of cetp -629c/a and i405v polymorphisms with coronary artery disease (...

برخورداری, عسگر, حسن‌زاده, تقی,

Background: Coronary heart disease (CHD) is a leading cause of death worldwide and hypertriglyceridemia and hypercholesterolemia are major risk factors for the disease. Considering the role of hyperlipidemia as the underlying cause of cardiovascular mortalities and morbidities, and the limited and conflicting results of studies on CETP gene polymorphisms in Iran, we aimed to study -971 G/A poly...

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